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Promising New Drug May Benefit Mesothelioma and Lung Cancer Patients

Ken Adler, a professor of cell biology at North Carolina State University developed a compound similar to a protein called a peptide. The peptide was developed to stop inflammation from spreading in patients suffering from lung problems such as chronic bronchitis or asthma. Adler, and long-time friend Reen Wu of the University of California-Davis, have now teamed up to see if this new peptide would stop cancer cells from spreading. Using this peptide, the spread of lung cancer or metastasis in mice was stopped. According to an article published in the News & Observer, Wu tested the peptide on human cancer cells last fall and remarked "Wow. We've never seen anything like this. It stops them from moving completely." The peptide inactivates actin, the main cable inside cells, which directs cell movement. According to Wu, "Inactivating actin prevents it from anchoring to the cell wall and keeps cells from moving."

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